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12. Jesus’ Entire Submission to His Father’s Will
(Matthew 26:42-46)
42Again, a second time, He went away and prayed, saying, “O My Father, if this cup cannot pass away from Me unless I drink it, Your will be done.”

Christ overcame the desire of His body through the Holy Spirit. He prayed His second prayer differently from the first one, in full harmony with God. The Son had recognized that there was no way to save the world but by the cross.
Woe to them who say that man will be justified by the acts of the law and not by the blood of Christ. Those do not partake of the redemption prepared for them, for Jesus alone drank the cup of wrath instead of us.
The Son overcame His own will during His second prayer. He agreed in compassion to drink instead of us the cup of the divine wrath, die as a sin sacrifice for sinners, and separate by the substitutionary atonement from His Father.
Prayer is not only the offering up of our desires to God, but is also the submitting of our will to his. It amounts to an acceptable prayer, when at any time we are in distress, to refer ourselves to our Father in heaven, and to commit our way and work to Him; “Your will be done.”